孟祥祺(副研究员,博士生导师 )



中山大学附属第六医院副研究员,分子医学博士生导师,百人计划引进人才。主要从事肿瘤发生、发展和转移的分子机制研究。相关研究成果荣获美国癌症研究协会(AACR)2014年度前列腺癌研究学者奖励(共3名),以及美国泌尿外科基础研究学会(SBUR)2016年奖学金,并被选中作大会正式报告。以第一或通讯作者身份先后在Nature communications, Advanced science, Gastroenterology, Oncogene 等杂志发表系列高水平科研文章。先后获得主持国家自然科学基金2项,广东省自然科学基金3项。


教育经历:
2004/09-2008/06,中山大学,生命科学学院,学士
2008/09-2013/06,中山大学,肿瘤防治中心,博士(硕博连读)


工作经历:
2013/09-2017/03,美国Van Andel 研究所,博士后
2017/06- 至今  ,中山大学附属第六医院,副研究员

代表性论文代表性项目荣誉

代表性论文(仅列举中科院一区的第一或通讯作者文章)
1)Jin, H.#, Huang,X.#, Pan, Q.#, Ma, N., Xie, X., Wei, Y., Yu, F., Wen W., Zhang, B., Zhang, P., Chen, X., Wang, J., Liu, R., Lin, J., Meng,X.* & Lee, M-H.*; The EIF3H-HAX1 axis increases RAF-MEKERK signaling activity to promote colorectal cancer progression, Nature Communications, 2024, Mar, 15(1):2551   (IF: 16.6)
2)Pan, Q.#, Yu, F.#, Jin, H.#, Zhang, P., Huang, X., Peng, J., Xie, X., Li, X., Ma, N., Wei, Y., Wen, W., Zhang, B., Zhang, J., Yu, H., Xiao, Y., Liu, R-Y., Liu, Q., Meng, X.* & Lee, M-H.*;eIF3f Mediates SGOC Pathway Reprogramming by Enhancing Deubiquitinating Activity in Colorectal Cancer,Advanced science,2023,Aug 6;e2300759. (IF:15.1)
3)Meng, X.#*, Peng, J.#, Xie, X.#, Yu, F., Wang, W., Pan, Q., Jin, H., Huang, X., Yu, H., Li, S., Feng, D., Liu, Q., Fang, L.*, & Lee, M.-H.*;Roles of lncRNA LVBU in regulating urea cycle/polyamine synthesis axis to promote colorectal carcinoma progression,Oncogene,2022,Sep;41(36):4231-4243. (IF:8.0)
4)Yu, H., Xie, M., Meng, Z., Lo, C. Y., Chan, F. L., Jiang, L., Meng, X.* & Yao, X.*;Endolysosomal ion channel MCOLN2 (Mucolipin-2) promotes prostate cancer progression via IL-1β/NF-κB pathway,British journal of cancer,2021,125:1420-1431. (IF:8.8)
5)Meng, X., Vander Ark, A., Daft, P., Woodford, E., Wang, J., Madaj, Z. & Li, X*;Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis,Cancer letters,2018,418:109-118. (IF:9.7)
6)Meng, X., Vander Ark, A., Lee, P., Hostetter, G., Bhowmick, NA., Matrisian, LM., Williams, BO., Miranti, CK., Li, X.*; Myeloid-specific TGF-β signaling in bone promotes basic-FGF and breast cancer bone metastasis, Oncogene, 2016, 35:2370-2378. (IF: 8.0)
7)Meng, X., Wu, J., Pan, C., Wang, H., Ying, X., Zhou, Y., Yu, H., Zuo, Y., Pan, Z., Liu, R., Huang, W.*; Genetic and Epigenetic Down-regulation of MicroRNA-212 Promotes Colorectal Tumor Metastasis via Dysregulation of MnSOD,Gastroenterology,2013,145:426-436. (IF:29.4)