Xiangling Yang(Research Assistant, Master Tutor)
2002-2006 B.S. Biotechnology, Guangdong Ocean University, Zhanjiang, China
2007-2012 Ph.D. Microbial and Biochemical Pharmacy, Sun Yat-sen University, Guangzhou,China
2014-present Research Assistant Guangdong Institute of Gastroenterology
Grant supports：
1. Jan.2015-Dec.2017 National Natural Science Foundation of China (Youth Program)
2. Aug.2015-Aug.2018 Guangdong Natural Science Foundation (PhD Start-up Fund)
3.Jan.2018-Dec.2021 National3. Natural Science Foundation of China (General Program)
Representative papersResearch directionHonor
1.Xiangling Yang, William W Du, Haoran Li, Fengqiong Liu, Anna Khorshidi, Zina Jeyapalan Rutnam, Burton B Yang*, Both Mature MiR-17-5p and Passenger Strand MiR-17-3p Target TIMP3 and Induce Prostate Tumor Growth and Invasion, Nucleic Acids Res, 2013, 41(21): 9688-9704.
2.Zhaoqun Deng#, Xiangling Yang#, Ling Fang, Zina J Rutnam, Burton B Yang*, Misprocessing and Functional Arrest of MicroRNAs by MiR-Pirate: Roles of MiR-378 and MiR-17, Biochem J, 2013, 450(2): 375-386.
3.Xiangling Yang, Zina Jeyapalan Rutnam, Chunwei Jiao, Duo Wei, Yizhen Xie, Jun Du, Ling Zhong, Burton B Yang*, An Anti-let-7 Sponge Decoys and Decays Endogenous Let-7 Functions, Cell Cycle, 2012, 11(16): 3097-3108.
4.Chuangyu Wen, Junxiong Chen, Di Zhang, Huihui Wang, Jia Che, Qiyuan Qin, LuHe, Zerong Cai, Mengmeng Lin, Qiong Lou, Lanlan Huang, Daici Chen, Aikichi Iwamoto, Donglin Ren, Lei Wang, Ping Lan, Jianping Wang, Huanliang Liu*, Xiangling Yang*, Pseudolaric Acid B Induces Mitotic Arrest and Apoptosis in Both 5-FU Sensitive and Resistant Colorectal Cancer Cells, Cancer Lett, 2016, 383(2): 295-308.
5.Junxiong Chen#, Chenliang Wang#, Wenjian Lan#, Chunying Huang, Mengmeng Lin, Zhongyang Wang, Wanling Liang, Aikichi Iwamoto, Xiangling Yang*, Huanliang Liu*, Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells, Mar Drugs, 2015, 13(10): 6259-6273.
6.Chuangyu Wen, Lanlan Huang, Junxiong Chen, Mengmeng Lin, Wen Li, Biyan Lu, Zina Jeyapalan Rutnam, Aikichi Iwamoto, Zhongyang Wang, Xiangling Yang*, Huanliang Liu*, Gambogic Acid Inhibits Growth, Induces Apoptosis, and Overcomes Drug Resistance in Human Colorectal Cancer Cells. Int J Oncol, 2015, 47(5):1663-1671.
7.Xiangling Yang, William W Du, Haoran Li, Fengqiong Liu, Anna Khorshidi, Zina Jeyapalan Rutnam, Burton B Yang*, Both Mature MiR-17-5p and Passenger Strand MiR-17-3p Target TIMP3 and Induce Prostate Tumor Growth and Invasion, Nucleic Acids Res, 2013, 41(21): 9688-9704.
8.Zhaoqun Deng#, Xiangling Yang#, Ling Fang, Zina J Rutnam, Burton B Yang*, Misprocessing and Functional Arrest of MicroRNAs by MiR-Pirate: Roles of MiR-378 and MiR-17, Biochem J, 2013, 450(2): 375-386.
9.Xiangling Yang, Zina Jeyapalan Rutnam, Chunwei Jiao, Duo Wei, Yizhen Xie, Jun Du, Ling Zhong, Burton B Yang*, An Anti-let-7 Sponge Decoys and Decays Endogenous Let-7 Functions, Cell Cycle, 2012, 11(16): 3097-3108.
10.Chuangyu Wen, Junxiong Chen, Di Zhang, Huihui Wang, Jia Che, Qiyuan Qin, LuHe, Zerong Cai, Mengmeng Lin, Qiong Lou, Lanlan Huang, Daici Chen, Aikichi Iwamoto, Donglin Ren, Lei Wang, Ping Lan, Jianping Wang, Huanliang Liu*, Xiangling Yang*, Pseudolaric Acid B Induces Mitotic Arrest and Apoptosis in Both 5-FU Sensitive and Resistant Colorectal Cancer Cells, Cancer Lett, 2016, 383(2): 295-308.
11.Junxiong Chen#, Chenliang Wang#, Wenjian Lan#, Chunying Huang, Mengmeng Lin, Zhongyang Wang, Wanling Liang, Aikichi Iwamoto, Xiangling Yang*, Huanliang Liu*, Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells, Mar Drugs, 2015, 13(10): 6259-6273.
12.Chuangyu Wen, Lanlan Huang, Junxiong Chen, Mengmeng Lin, Wen Li, Biyan Lu, Zina Jeyapalan Rutnam, Aikichi Iwamoto, Zhongyang Wang, Xiangling Yang*, Huanliang Liu*, Gambogic Acid Inhibits Growth, Induces Apoptosis, and Overcomes Drug Resistance in Human Colorectal Cancer Cells. Int J Oncol, 2015, 47(5):1663-1671.
Study on mechanism of colorectal cancer development and anticancer drug development
