Xiangqi Meng (Associate Professor)
09/01/2004—06/2008 Sun Yat-sen University, B.S.
09/01/2008---06/2013 Sun Yat-sen University, Ph.D.
09/01/2013—03/31/2017，Van Andel Research Institute, America, Postdoctoral fellow
06/01/2017—Present, Associate Professor, the 6th affiliated Hospital, Sun Yat-sen University
Project:
Osteoblast (osteoclast) specific TGF-β signaling in prostate (breast) cancer bone metastasis
Representative papersResearch directionHonor
1. Meng XQ*, Vander Ark A., Lee P., Hostetter G., Bhowmick N.A., Matrisian L.M., Williams B.O., Miranti C.K., & Li XH#. Myeloid-specific TGF-β signaling in bone promotes basic-FGF and breast cancer bone metastasis. Oncogene. 2015;35（18）：2370~2378
2. Meng XQ*, Wu JX, Pan CC, Wang H, Ying XF, Zhou Y, Yu HY, Zuo YF, Pan ZZ, Liu RY, & Huang WL#. Genetic and Epigenetic Downregulation of MicroRNA-212 Promotes Colorectal Tumor Metastasis via Dysregulation of MnSOD. Gastroenterology. 2013;145(2):426-36.e1-6
3. Yu HY*, Meng XQ*, Wu JX, Pan CC, Ying XF, Zhou Y, Liu RY, & Huang WL#. Cryptochrome 1 overexpression correlates with tumor progression and poor prognosis in patients with colorectal cancer. Plos One. 2013;23;8(4):e61679.
4. Zeng Q*, Hong MH, Shen LJ, Meng XQ, Guo X, Qian CN, Wu PH & HuangPY#. Nomograms for predicting long-term survival in patients with non-metastatic nasopharyngeal carcinoma in an endemic area. Oncotarget. 2016;7(20):29708-19
5. Yu HY*, Ye W, Wu JX, Meng XQ, Liu RY, Ying XF, Zhou Y, Wang H, Pan CC, & Huang WL#. Overexpression of Sirt7 exhibits oncogenic property and serves as a prognostic factor in colorectal cancer. Clinical Cancer Research. 2014;20(13), 3434-3445.
6. Zhou Y*, Wu JX, Fu X, Du WY, Zhou L, Meng XQ, Yu HY, Lin JX, Ye W, Liu JN, Peng H, Liu RY, Pan CC, & Huang WL#. OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer. Molecular Cancer. 2014;13(1), 1-14
7. Ying XF*, Wu JX, Meng XQ, Zuo YF, Xia Q, Chen J, Feng Y, Liu RY, Li LR, & Huang WL#. AC133 expression associated with poor prognosis in stage II colorectal cancer. Medical Oncology. 2013;30(1):356
8. Wang H*, Wu JX, Meng XQ, Ying XF, Zuo YF, Liu RY, Pan ZZ, Kang TB, & Huang WL#. MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. Carcinogenesis. 2011;32(7):1033-42
9. Zuo YF*, Wu JX, Xu ZM, Yang SP, Yan HJ, Tan L, Meng XQ, Ying XF, Liu RY, Kang TB, & Huang WL#. Minicircle-oriP-IFNγ: a novel targeted gene therapeutic system for EBV positive human nasopharyngeal carcinoma. PLoS One. 2011;5; 6(5):e19407.
The National Science Foundation, ￥200,000，81702533, 01/2018—12/2020
1. Meng Xiangqiqi, 2014 AACR (American Association for Cancer Research)-Prostate Cancer Foundation Scholar-in-Training Award
2. Meng Xiangqi, 2016 SBUR (Society for Basic Urologic Research) Travel Award
3. Pioneer Hundred Talents Program of SYSU
