CHINESE

Lekun Fang(Associate professor, doctoral supervisor)

Representative papersResearch directionHonor
1.Fang L#, Lu W#, Choi HH, Yeung SC, Tung JY, Hsiao CD, Fuentes-Mattei E, Menter D, Chen C, Wang L, Wang J*, Lee MH*. ERK2-dependent phosphorylation of CSN6 is critical in colorectal cancer development. Cancer Cell ;2015, 28(2):183-197
2.Fang L#, Yang Z#, Zhou J, Tung JY, Hsiao CD, Wang L, Deng Y, Wang P, Wang J*, Lee MH*. FBXW7 is involved in CRY2 degradation and Regulates Tumor Response to Chemotherapy in Colorectal Cancer. Molecular Cancer therapeutics. 2015,14(6):1476-1487
3.Fang L#, Li H#, Wang L, Hu J, Jin T, Wang J*, Yang BB*. MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression. Oncotarget. 2014,5(10):2974-2987
4.Huang D#, Lu W#, Zou S, Wang H, Jiang Y, Zhang X, Li P, Songyang Z, Wang L, Wang J, Huang J*, Fang L*. RhoGDIα is a potential prognostic biomarker and controls telomere regulation in colorectal cancer. Cancer Science. 2017 108(7):1293-1302.
5.Xiang J#, Fang L#, Luo Y, Yang Z, Liao Y, Cui J, Huang M, Yang Z, Huang Y, Fan X, Wang H, Wang L, Peng J, Wang J. Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer. J Transl Med. 2014,12(1):320