Ping Yuan(Researcher, Doctoral Tutor)

1.Sun, X.*， Ren, Z.*， Cun, Y.， Zhao, C.， Huang, X.， Zhou, J.， Hu, R.， Su, X.， Ji, L.， Li, P.， Mak, K.K.， Gao, F.，Yang, Y.， Xu, H.， Ding, J.， Cao, N.， Li, S.， Zhang, W.， Lan, P.， Sun, H.， Wang, J#.， Yuan,P.# Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers. Nucleic Acids Res.(2020) Jun 8;gkaa482. doi: 10.1093/nar/gkaa482. 

2. Huang, D.*,Guo, G.*, Yuan, P.*, Ralston, A.*, Sun, L., Huss, M., Mistri, T., Pinello, L., Ng, H.H., Yuan, G., Ji, J., Rossant, J.#, Robson, P.#and Han, X#. The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during trophectoderm and inner cell mass specification. Sci Rep, (2017), 7(1):17156；doi: 10.1038/s41598-017-16009-w. 

3.Li, P., Ma, X., Adams, I. and Yuan, P.# A tight control of Rif1 by Oct4 and Smad3 is critical for mouse embryonic stem cell stability,  Cell Death Dis , (2015)，6: e1588; doi:10.1038/cddis.2014.551. 

4.Han, J., Yuan, P., Yang, H., Zhang, J., Yay, J., Soh, B.S., Li, P., Lim, S.L., Orlov, Y., Luftkin, T., Ng, H.H., Tam, W.L. and Lim, B. Tbx3 improves the germ-line competency of induced pluripotent stem cells. Nature (2010), 463(7284), 1096-1100 

5.Yuan, P.*, Han, J.*, Guo, G., Orlov, Y.L., Huss, M., Loh, Y.H., Clarke, N., Robson, P., Lim, Bing. and Ng, H.H. Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes  Dev (2009), 23(21), 2507-2520. 

6. Chen, X.*, Han, X.*, Yuan, P., Fang, F., Huss, M., Vega, V.B., Wong, E., Orlov, Y.L., Zhang, W., Jiang, J., Loh, Y.H., Yeo, H.C., Yeo, Z.X., Narang, V., Govinfarajan, K.R., Leong, B., Shahab, A., Ruan, Y., Bourque, G., Sung, W.K., Clarke, N.D., Wei, C.L. and Ng, H.H. Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells. Cell, (2008), 133, 1106-1117. 

7.Saxena, S.*, Yuan, P.*, Dhar, S.K.*, Senga, T., Takeda, D., Robinson, H., Kornbluth, S., Swaminathan, K. and Dutta, A  A dimerized coiled coil domain and an adjoining part of Geminin interact with two sites on Cdt1 for replication inhibition. Mol Cell, (2004), 15(2), 245-258. 

8.Yuan, P., Jedd, G., Kumaran, D., Swaminathan, S., Chua, N.H. and Swaminathan, K. A HEX-1 crystal lattice required for Woronin body function in Neurosporal Crassa. Nat Struct Biol  (2003), 10(4), 264 -270. 

Prof. YUAN Ping’s research lies in functional genomics and stem cell biology. She aims at understanding novel coordinated interactions between transcriptional and epigenetic mechanisms in early embryo development, self-renewal and differentiation of pluripotent stem cells and cancer stem cells. She also explores the application potential of the novel mechanisms in cell therapy and cancer treatment. She has published her researches in a number of high impact journals, such as Cell, Nature, Molecular Cell, Genes & Development, Nature Structural Biology，Cell Death & Disease and Nucleic Acids Research etc. The total SCI citation of her research papers is above 2300 times. She is the principle investigator of projects funded by Leukemia and Lymphoma foundation USA, National Natural Science Foundation of China and the University Grants Committee of Hong Kong SAR. She serves as a reviewer for multiple international journals, such as Stem Cells, Nanoscale and Journal of Genetics and Genomics, etc

2017  “Hundred-talent Award Program” of Sun Yat-sen University
2011 The Global Scholarship program for Research Excellence –CNOOC 2010-11, the Chinese University of Hong Kong
2005  Research Fellowship from Leukemia and Lymphoma Society, USA